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MCC950

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MCC950

查看23 家供应商

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CAS No. 210826-40-7

分子式 C20H24N2O5S

分子量 404.48

英文名称 MCC950

中文同义词化合物MCC950

基本信息

产品名称

MCC950

中文同义词

化合物MCC950

英文名称

MCC950

英文同义词

N-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl)-4-(2-hydroxypropan-2-yl)furan-2-sulfonamid;MCC950;N-[[(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-2-furansulfonamide;N-[[(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-2-furansulfonamChemicalbookide;2-Furansulfonamide, N-[[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-;1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[4-(2-hydroxypropan-2-yl)furan-2-yl]sulfonylurea;MCC950 (MCC-950;CS-2292

CAS No.

210826-40-7

分子式

C20H24N2O5S

分子量

404.48

EINECS号

604-604-1

MDL NO.

MFCD28900720

MOL

210826-40-7.mol

性质

密度

1.396±0.06 g/cm3(Predicted)

形态

solid

熔点

239 °C

颜色

White

储存条件

-20°C

酸度系数(pKa)

4.74±0.10(Predicted)

溶解度

Soluble in DMSO (up to 40 mg/ml) or in Water (up to 30 mg/ml)

稳定性

Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.

用途

靶点

TargetValue NLRP3 (BMDM-based assay) 7.5 nM NLRP3 (HMDM-based assay) 8.1 nM

生物活性

MCC950 (CP-456773, CRID3) 是一种有效的 NLRP3 (NOD-like receptor (NLR) family, pyrin domain-containing protein 3) 的选择性抑制剂，在BMDMs和HMDMs中对应的IC50值分别为7.5 nM和8.1 nM。

安全信息