gramicidin from bacillus brevis*(gramicidin D);Gramicidin micronized USP23;GramicidinN.F.Xiv;gramicidin from bacillus aneurinolyticus (bacillus brevis);GRAMICIDIN,USP;GRAMACIDIN D;GRAMICIDIN;GRAMICIDIN D [DUBOS]
Practically insoluble in water, soluble in methanol, sparingly soluble in alcohol
水溶解性
Soluble in acetic acid and lower alcohols. Practically insoluble in water.
用途
靶点
Bacterial
体外研究
Gramicidin is an antimicrobial peptide assembling as channels in membranes and increasing their permeability towards cations. There is poor Gramicidin activity against
E. coli
and
S. cerevisae
as shown from the survival of microbes (%) over a range of Gramicidin concentrations, in contrast with the action of Gramicidin on
S. aureus
. The microbicidal activity occurs over a range of low Gramicidin and DODAB concentrations which are not toxic to
S. cerevisae
.
编辑结构
