Stable. Incompatible with strong oxidizing agents.
CAS 数据库
13721-39-6(CAS DataBase Reference)
EPA化学物质信息
Sodium vanadium oxide (Na3VO4) (13721-39-6)
用途
应用
钒酸钠属于无机盐化合物，主要用作催化剂、油漆催干剂、媒染剂、缓蚀剂等，也用于制备其他钒盐。
用途
几种磷酸酶和磷酸激酶的抑制剂
靶点
PPTPase.
体外研究
In the presence of oxidizing agents vanadium ions exist as the hydrated monomer of Sodium orthovanadate (vanadate: HVO4
2-
or H2VO
4-
) at micromolar concentations near neutral pH. Sodium orthovanadate (vanadate) also begins to polymerize at concentrations greater than 0.1 mM at neutral pH. The yellow-orange solutions of decavanadate can be converted to the colorless solutions of monomeric Sodium orthovanadate (vanadate) by dilution after a period of many hours. The process is hastened by boiling at pH 10, which encourages the kinetically sluggish depolymerization process. Sodium orthovanadate could alter the phosphorylation status of ASK1 at serine 83 and threonine 845 induced by ischemia. Sodium orthovanadate could increase the tyrosine posphorylation of PTEN and further inhibit the activation of ASK1 via activating Akt during cerebral ischemia.
编辑结构
