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124447-81-0
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CAS No. 124447-81-0
分子式 C167H272N52O53S2
分子量 3920.39318
英文名称 Amylin (mouse, rat)
中文同义词 RAT AMYLIN;胰淀素受体AMYLIN, AMIDE, RAT
基本信息
产品名称
124447-81-0
中文同义词
RAT AMYLIN,胰淀素受体AMYLIN, AMIDE, RAT
英文名称
Amylin (mouse, rat)
英文同义词
Amylin (mouse, rat);AMylin (Mouse, rat) IAPP (Mouse, rat), Islet aMyloid polypeptide (Mouse, rat);H-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Pro-Val-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2;IAPP (Mouse, rat), Islet aMyloid polypeptide (Mouse, rat);Amylin (mouse, rat) trifluoroacetate salt H-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Pro-Val-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2 trifluoroacetate salt (Disulfide bond);Ratamylin;Amylin, amide, rat acetate
CAS No.
124447-81-0
分子式
C167H272N52O53S2
分子量
3920.39318
EINECS号
-
MDL NO.
-
性质
形态
固体
颜色
白色至米白色
用途
靶点
Amylin receptor AMY1 and AMY3
体外研究
Amylin is an important, but poorly understood, 37 amino acid glucoregulatory hormone with great potential to target metabolic diseases. Amylin is a member of the calcitonin (CT) family of peptides, which includes CT itself, the CGRPs comprising two variants (αCGRP and βCGRP), adrenomedullin (AM) and AM2 (intermedin). Amylin is a centrally acting, neuroendocrine hormone synthesized with insulin in the beta cells of pancreatic islets. Amylin regulates glucose homeostasis by inhibiting gastric emptying, inhibiting the release of the counter-regulatory hormone glucagon and inducing meal-ending satiety. Amylin functions as a glucoregulatory and satiety-inducing hormone, which is protective against postprandial spikes in blood glucose and overeating.
生物活性
Amylin, amide, rat 是一种有效的高亲和力的胰淀素受体 AMY1 和 AMY3 的配体。
编辑结构
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中文名称:
124447-81-0
英文名称:
Amylin (mouse, rat)
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124447-81-0
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中文名称:
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Amylin (mouse, rat)
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124447-81-0
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英文名称:
Amylin (mouse, rat)
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124447-81-0
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