Solubility in hot methanol, very faint turbidity. Soluble in dichloromethane, chloroform.
CAS 数据库
2316-26-9(CAS DataBase Reference)
NIST化学物质信息
3,4-Dimethoxycinnamic acid(2316-26-9)
用途
用途
用于医药中间体及有机合成中间体
体外研究
3,4-Dimethoxycinnamic acid (Methyl ferulic acid; 25, 50 and 100 µM) attenuates the ethanol-induced apoptosis of ethanolexposed L-02 cells.
3,4-Dimethoxycinnamic acid (25, 50 and 100 µM) inhibits the expression levels of Nox4 and p22
phox
in L-02 cells.
3,4-Dimethoxycinnamic acid (25, 50 and 100 µM) treatment attenuates ethanol-induced MAPK phosphorylation in L-02 cells.
3,4-Dimethoxycinnamic acid decreases the expression levels of superoxide dismutase, catalase and phospholipid hydroperoxide gluthione peroxidase, and downregulates the levels of Bax/Bcl-2 and the cleaved forms of caspase-3 in a dose- and time-dependent manner.