体外研究
KN-93 (5-50μM; 24 hours) inhibits LX-2 cell growth and KN-92 (5-50μM; 24 hours) is ineffective in blocking cell growth.
The analysis of cell cycle regulator expression reveals that KN-93 rather than KN-92 reduced the expression of p53 and p21.
Cell Viability Assay
Cell Line:
Human hepatic stellate cells (LX-2)
Concentration:
5-50 μM
Incubation Time:
24 hours
Result:
Ineffective in blocking cell growth.